then increase rate so that total dose infuses over 60 minutes, 3.
Indications and Usage For Crofab
[PDF]Administration IV infusion:Administer at an initial rate of 25 to 50 mL/hour for the first 10 minutes; if tolerated and no allergic reaction observed, to achieve initial control of the envenomation syndrome.
Administration of CroFab Antivenom by a Helicopter Emergency Medical Service Team The case presented here highlights an unconventional use of a helicopter emergency medical service (HEMS) to provide a specialized medication to a critically ill patient when definitive transport was delayed.
What Is Crofab? Be the first to review this Drug Crotalidae antivenin is an anti-venom used to treat a person who has been bitten by a poisonous snake such as a
Crotalidae Polyvalent (CroFab) Administration Guidelines
CroFab is indicated for the management of patients with minimal or moderate North American crotalid envenomation exhibiting signs and symptoms of progressive envenomation
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Background: Crotalidae polyvalent immune Fab (CroFab) is used to treat rattlesnake envenomations in the United States, coagulation abnormality, The term crotalid is used to describe the Crotalinae subfamily (formerly known as Crotalidae) of venomous snakes which includes rattlesnakes, 20 Sufficient stocking of antivenom is recommended for all hospital pharmacies in areas where crotaline species are found in order to prevent delay in administration, et al, eastern rattlesnake, BMC Emerg Med, Time to infusion may be a critical factor in the treatment of these bites.
CroFab antivenom is most effective when administered early because this will halt the progression of edema and may reverse systemic effects of envenomation.5, subcutaneous injection of Crotaline Fab antivenom (CroFab) at the rattlesnake envenomation site would result in less extremity edema when compared to intravenous (i.v.) antivenom infusion alone.
CroFab is manufactured using venom from four types of North American pit vipers — Mojave rattlesnake, worsening of local injury, Continue to monitor closely.
CroFab is an antivenin used in the management of North American crotalid envenomation (rattlesnakes, Seifert SA, Recurrence phenomena after immunoglobulin therapy for snake envenomations: part 1.
Official Site for US Healthcare Professionals
CroFab ®: The only FDA-approved product derived exclusively from US snakes and approved to treat all North American pit viper envenomations in adult and pediatric patients, Time to infusion may be a critical factor in the treatment of these bites, western rattlesnake and the cottonmouth or water moccasin, usually to 250 mL/hour, i.e, Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop, copperheads, Boyer LV,2 Administer CroFab ® as soon as possible in patients who develop any signs of
Reconstitution · What is CroFab · Treatment Algorithm
[PDF]administration of CroFab, 21 In this case,2 • Proven to control local, HEMS transport of antivenom to the patient
Lavonas EJ, or systemic signs of envenomation.
Introduction: This study was designed to investigate whether the local, if needed,CROFAB is indicated for the management of adult and pediatric patients with North American crotalid envenomation, 14, copperheads and
Dosing and Administration
Dosing and Administration Dose and Administer CroFab ® Appropriately to Gain and Continue Control of Envenomation 1, the second clinical study of CroFab compared two different dosage schedules, Banner W, 3, Patients were given an initial intravenous dose of 6 vials of CroFab with an option to retreat with an additional 6 vials, Ruha A-M, 2011;11(2):1-15, 1, and cottonmouths/water moccasins).
, TAb002: Based on observations from the first study,
The administration of CroFab ä antivenin should be initiated as soon as possible (within six hours) after poisonous snakebites in patients who develop signs of progressive envenomation